Figure 6.

Decreases in circulating ectonucleotidase activity in Crohn’s disease. A. A comparison of total plasma ectonucleotidase activities. Samples from 28 Crohn’s [CD] patients and 14 healthy controls were analysed. B. The ectonucleotidase activity in the presence of inhibitors Ap5A [adenylate kinase 1], POM1 [CD39 and NTPDase3], and POM6 [NTPDase2, and -3]. C. A comparison of POM1- and POM6-sensitive ectonucleotidase activities between controls and Crohn’s patients. D. A comparison of POM1- and POM6-sensitive ectonucleotidase activities between Crohn’s patient with HBI 1–3 and with HBI > 3; p-values are calculated using Student’s t test and labelled with asterisks: *p < 0.05, **p < 0.01, ***p < 0.001.