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. 2018 Mar 19;41(6):3405–3421. doi: 10.3892/ijmm.2018.3574

Figure 6.

Figure 6

ST1926 suppresses Toll-like receptor 4 (TLR4)/MyD88 signal pathway to inactivate nuclear factor-κB (NF-κB) activity. (A) TLR4 and MyD88 protein levels were evaluated through western blot analysis. (B) The quantification of TLR4 and MyD88 is shown following immunoblotting analysis. (C) RT-qPCR was used to determine TLR4 and MyD88 gene levels. (D) Immunofluorescence was included to further test TLR4 expression levels. The data are presented as mean ± SD (n=8). *p<0.05 and **p<0.001 vs. the control (Con); +p<0.05, ++p<0.01 and +++p<0.001 vs. lipopolysaccharide (LPS)-induced mice (LPS).