Figure 7.

ST1926 impedes oxidative stress in mice with acute lung injury induced by lipopolysaccharide (LPS). (A) SOD activity, CAT activity and MDA levels were measured in the serum of mice after LPS induction in the absence or presence of ST1926 at different doses. (B) SOD activity, CAT activity and MDA levels were measured in the lung tissue samples of mice after LPS induction in the absence or presence of ST1926 at different doses. (C) O₂⁻ and H₂O₂, as well as nitrate levels in the LPS-induced lung tissue samples were measured. The data are presented as mean ± SD (n=8). ^*p<0.05 and ^**p<0.001 vs. the control (Con); ⁺p<0.05, ⁺⁺p<0.01 and ⁺⁺⁺p<0.001 vs. LPS-induced mice (LPS).