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. 2018 Mar 19;41(6):3405–3421. doi: 10.3892/ijmm.2018.3574

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Copyright: © Dong et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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ST1926 reduced reactive oxygen species (ROS) generation from iNOS/MPO inhibition. (A) NOx levels in the lung tissue samples were examined. (B) MPO activity was measured in the lung tissue specimens obtained from mice pre-treated with lipopolysaccharide (LPS) and/or ST1926 under different conditions. (C) The representative images of iNOS and MPO assessed by western blot analysis and the quantification was shown. The data are represented as mean ± SD (n=8). ^*p<0.05 and ^**p<0.001 vs. the control (Con); ⁺p<0.05, ⁺⁺p<0.01 and ⁺⁺⁺p<0.001 vs. LPS-induced mice (LPS).