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. 2018 Mar 7;41(6):3115–3126. doi: 10.3892/ijmm.2018.3541

Figure 3.

Figure 3

Aurora B impacts the viability related proteins and genes. (A) The protein levels of p-p38 MAPK, CDK4, PCNA, Fas, caspase-8, caspase-3, Bcl-2 were performed by western blotting. (B) Scanning intensities of western blotting are shown. (C) The mRNA levels of cdk4, PCNA, caspase-3 and bcl-2 were determined using RT-qPCR. Each experiment was repeated three times, and the values are presented as the mean ± standard devidation; *P<0.05, **P<0.01 and ***P<0.001 cf. the 0 μM values. p-p38 MAPK, p-p38 mitogen-activated protein kinase; CDK4, cyclin-dependent kinase 4; PCNA, proliferating cell nuclear antigen; Bcl-2, B-cell lymphoma 2.