Table 3.
Baseline predictor | CD-related surgery | CD-related complication a | ||||
---|---|---|---|---|---|---|
Regression coefficientb | SE | p-value | Regression coefficientc | SE | p-value | |
Intercept | -3.607 | 0.327 | -1.6134 | 0.162 | ||
Age subtract 45 years | -0.0027 | 0.007 | 0.72 | -0.0102 | 0.004 | 0.02 |
Male vs female | 0.3946 | 0.194 | 0.06 | -0.1848 | 0.110 | 0.13 |
HBI score [except stool frequency] | 0.2425 | 0.065 | < 0.001 | 0.1139 | 0.042 | 0.01 |
Stool frequencyd | 0.0741 | 0.060 | 0.25 | 0.0752 | 0.034 | 0.04 |
Location of disease involvement | ||||||
Colon only [reference] | 0 | – | – | 0 | – | – |
Small bowel and colon | 0.3614 | 0.293 | 0.26 | 0.2525 | 0.145 | 0.12 |
Small bowel only | 0.5167 | 0.297 | 0.11 | 0.1739 | 0.153 | 0.31 |
Corticosteroid use | – | – | – | 0.2465 | 0.138 | 0.11 |
Anti-metabolite use | -0.4519 | 0.200 | 0.04 | -0.1598 | 0.110 | 0.19 |
5-aminosalicylate use | -0.6015 | 0.253 | 0.03 | – | – | – |
TNF antagonist use | – | – | – | 0.3887 | 0.114 | < 0.01 |
Presence of new fistula, abscess, or definite abdominal mass | 1.7019 | 0.306 | < 0.0001 | 1.0840 | 0.261 | < 0.001 |
Interaction | ||||||
HBI score × stool frequency | -0.0182 | 0.014 | 0.22 | -0.0136 | 0.009 | 0.18 |
SE, standard error; CD, Crohn’s disease; HBI, Harvey-Bradshaw Index; TNF, tumour necrosis factor.
aComplication refers to the first occurrence of a CD-related surgery, complication, or hospitalisation.
bRegression coefficients are presented before shrinkage [shrinkage factor = 0.92].
cRegression coefficients are presented before shrinkage [shrinkage factor = 0.90].
dStool frequency has a maximum value of 12.