. Author manuscript; available in PMC: 2018 Apr 3.

Published in final edited form as: J Perinat Med. 2015 Jan;43(1):19–36. doi: 10.1515/jpm-2014-0249

Table 3.

Inflammatory markers in maternal blood, amniotic fluid, and umbilical cord in patients with clinical chorioamnionitis at term according to the results of amniotic fluid cultures and PCR/ESI-MS

	No inflammation/infection (n=7)	p- value^a	Intra-amniotic inflammation without detectable microorganisms (n=11)	p-value^b	Microbial-associated intra-amniotic inflammation (n=25)	p-value^c
Maternal white blood cell count (10³/mm³)	15 (10.6 – 16.8)	0.3	15.3 (13.7 – 17.8)	0.2	16.7 (13.1 – 21)	0.04
Maternal blood IL-6 (pg/mL)	18.8 (11.7 – 37.7)	0.1	4.6 (0.9 – 29)	0.1	9.4 (5.4 – 45.5)	0.3

AF white blood cell count (cells/mm³)	5 (0 – 42)	0.6	25 (0 – 85)	0.03	300 (39 – 900)	0.003
AF glucose (mg/dL)	9 (9 – 12)	1	9 (9 – 10)	0.04	9 (7 – 9)	0.3
AF IL-6 (ng/mL)	0.9 (0.4 – 1)	<0.001	4.7 (3.2 – 15)	0.06	14.1 (5.7 – 36.8)	<0.001

Cord blood IL-6 (pg/mL)	2.6 (1.9 – 5.8)	0.4	4.3 (2.3 – 6.2)	0.1	6.5 (2.5 – 23.2)	0.1

Data presented as median (interquartile) and percentage and (n); AF: amniotic fluid; IL: interleukin

Comparison between no inflammation/infection and intra-amniotic inflammation without detectable microorganisms.

Comparison between patients with intra-amniotic inflammation without detectable microorganisms and microbial-associated intra-amniotic inflammation.

Comparison between patients with no inflammation and microbial-associated intra-amniotic inflammation.