|
Same donor as first |
(v. different donor) |
2.31 |
0.77 |
6.92 |
0.16 |
|
Performed 2005–2009 |
(v. 2010–2015) |
1.82 |
0.65 |
5.0 |
0.28 |
|
Age > 45 |
(v. <45) |
1.8 |
0.73 |
4.42 |
0.19 |
|
Refractory or Progressive Disease |
(v. CR or PR) |
2.56 |
1.03 |
6.25 |
0.06 |
|
Relapse diagnosed within 6 months |
(v. > 6 months) |
2.49 |
1.0 |
6.2 |
0.07 |
|
Acute GVHD from first transplant |
(v. no GVHD) |
2.12 |
0.87 |
5.17 |
0.11 |
|
Second graft contained new haplotype |
(v. no new haplotype) |
0.36 |
0.14 |
0.9 |
0.02 |
EFS |
|
|
|
|
|
|
|
Same donor as first |
(v. different donor) |
1.54 |
0.52 |
4.5 |
0.46 |
|
Performed 2005–2009 |
(v. 2010–2015) |
1.89 |
0.2 |
1.44 |
0.25 |
|
Age > 45 |
(v. <45) |
2.32 |
0.99 |
5.44 |
0.05 |
|
Refractory or Progressive Disease |
(v. CR or PR) |
2.44 |
1 |
5.88 |
0.07 |
|
Relapse diagnosed within 6 months |
(v. > 6 months) |
2.53 |
1.03 |
6.22 |
0.06 |
|
Acute GVHD from first transplant |
(v. no GVHD) |
1.50 |
0.65 |
3.44 |
0.35 |
|
Second graft contained new haplotype |
(v. no new haplotype) |
0.50 |
0.22 |
1.14 |
0.09 |
Cumulative Incidence of Relapse |
|
|
|
|
|
|
Same donor as first |
(v. different donor) |
0.76 |
0.13 |
4.51 |
0.77 |
|
Performed 2005–2009 |
(v. 2010–2015) |
1.11 |
0.23 |
5.26 |
0.89 |
|
Age > 45 |
(v. <45) |
5.29 |
1.13 |
24.74 |
0.03 |
|
Refractory or Progressive Disease |
(v. CR or PR) |
1.67 |
0.45 |
6.25 |
0.44 |
|
Relapse diagnosed within 6 months |
(v. > 6 months) |
1.43 |
0.38 |
5.41 |
0.59 |
|
Acute GVHD from first transplant |
(v. no GVHD) |
0.44 |
0.1 |
1.87 |
0.27 |
|
Second graft contained new haplotype |
(v. no new haplotype) |
0.81 |
0.25 |
2.59 |
0.73 |
Cumulative Incidence of Non-Relapse Mortality |
|
|
|
|
|
|
Same donor as first |
(v. different donor) |
2.62 |
1.02 |
6.71 |
0.05 |
|
Performed 2005–2009 |
(v. 2010–2015) |
1.79 |
0.44 |
7.14 |
0.42 |
|
Age > 45 |
(v. <45) |
1.09 |
0.38 |
3.18 |
0.87 |
|
Refractory or Progressive Disease |
(v. CR or PR) |
2.08 |
0.66 |
6.67 |
0.21 |
|
Relapse diagnosed within 6 months |
(v. > 6 months) |
2.09 |
0.61 |
7.2 |
0.24 |
|
Acute GVHD from first transplant |
(v. no GVHD) |
3.44 |
1.19 |
9.94 |
0.02 |
|
Second graft contained new haplotype |
(v. no new haplotype) |
0.4 |
0.12 |
1.32 |
0.13 |