Table 3.

STIM2 interacting proteins.

Binding Protein	Identity of binding protein	Cell type/in vitro method	Reference
Cytoskeletal/cell surface
EB1 and EB3	Microtubule binding proteins	HEK293, HeLa	58
PI(4,5)P2	Membrane phospholipid	Lipid-binding assay	59
GluA1 and GluA2	AMPA receptor subunit	Hippocampal neurons, rat cortical neurons	60,61
Spectrin α and β chains	Scaffold protein	MIN6,NIH 3T3	***
SOCE proteins
STIM1	ER Ca2+ sensor	HEK293, HEK293T, Human platelets, HeLa, NIH 3T3	64,65,98,112
Orai1	CRAC channel	Human Platelets, rat cortical neurons, mouse dendritic cells, HEK293	63,66,68,69
Orai2	Store-operated Ion Channel	Mouse dendritic cells	66
TRPC3	Non-selective cation channel	HUVEC
Nuclear transport
Exportin1	Nuclear export	HEK293T	77
Transportin1	Nuclear import	HEK293T	77
ER Proteins
IP3R1	ER Ca2+ channel	BAECs	79
SERCA3	ER Ca2+ ATPase	Human Platelets	63
Calnexin	ER chaperone/MAM protein	HEK293T	77
GRP78/BiP	ER chaperone	NIH 3T3	***
Others
Calmodulin	Ca2+ binding protein	CaM binding assay, isothermal titration calorimetry	59,87
AKAP	Scaffold protein	Hippocampal neurons	60
rPKA and cPKA	PKA subunits	Hippocampal neurons	60
PRKAA2	Energy sensor	HEK293T	88
Liprin-alpha-1, 2, and 3	Focal adhesion regulator	MIN6, NIH 3T3	***
Heat Shock Cognate 71 kDa protein	Molecular chaperone	NIH 3T3	***
Rab11 family-interacting protein	Endosomal recycling	NIH 3T3	***

***Nelson HA and Roe MW: unpublished observations.