Figure 5.

Localization of estrogen receptors. Estrogen receptors α (ERα) and ERβ are examined through immunohistochemistry. The young group showed low intensity for both receptors. The dilated renal tubules (asterisks) show strong positive reactions, and ERα and ERβ localize to the nucleus and cytoplasm of epithelial cells, respectively. Dilated renal tubules also contain the negative cells (arrows). These reactions are faint in ovariectomy (OVX) groups. (A color version of this figure is available in the online journal.)