. 2018 Mar 28;14:1744806918767512. doi: 10.1177/1744806918767512

Table 7.

Between-group comparisons of ΔBOLD at six significant ROIs.

Name of ROIs	Levene’s test		Group	ΔBOLD		t	df	p
Name of ROIs	F value	p	Group	Mean (%)	SE (%)	t	df	p
Putamen	0.190	0.665	HC	0.204	0.071	3.899	32	<0.0005*
Putamen	0.190	0.665	CP	−0.225	0.084	3.899	32	<0.0005*
ACC	0.157	0.695	HC	0.107	0.032	5.51	32	<0.0005*
ACC	0.157	0.695	CP	−0.138	0.030	5.51	32	<0.0005*
dlPFC	0.606	0.442	HC	0.085	0.045	2.905	32	0.007*
dlPFC	0.606	0.442	CP	−0.175	0.078	2.905	32	0.007*
Brainstem	4.205	0.049*	HC	0.153	0.052	3.522	24.34	0.002*
Brainstem	4.205	0.049*	CP	−0.240	0.099	3.522	24.34	0.002*
mPFC	6.764	0.014*	HC	0.094	0.030	4.340	21.44	<0.0005*
mPFC	6.764	0.014*	CP	−0.242	0.072	4.340	21.44	<0.0005*
				Median (%)	Interquartile range			p
NAc	–	–	HC	0.054	−0.052 to 0.276			0.008†
NAc	–	–	CP	−0.175	−0.467 to 0.052

Only data at the NAc showed nonnormal distribution. Statistical analysis was accordingly performed with a Mann–Whitney’s U test † for NAc or an unpaired t test * for the rest. Inhomogeneity of variance was found for Brainstem and mPFC data sets after a Levene’s test.

BOLD: blood oxygenation level-dependent; ROI: region of interest; HC: healthy control; CP: patients with chronic pain; SE: standard error of the mean; df: degree of freedom; ACC: anterior cingulate cortex; dlPFC: dorsolateral prefrontal cortex; mPFC: medial prefrontal cortex; NAc: nucleus accumbens.