Table 8.

Correlations among %ΔOA, ΔBOLD, and psychophysical parameters in HC and CP.

Brain activity	Name of ROIs	Group	%ΔOA		PD-Q		PCS		BDI		SF-MPQ		VAS		Duration
			R	p	R	p	R	p	R	p	R	p	R	p	R	p
ΔBOLD	Putamen	HC	0.250	0.333	−0.135	0.676	–	–	0.561	0.019*	0.238	0.358	–	–	–	–
		CP	−0.156	0.550	−0.343	0.178	−0.184	0.481	−0.317	0.215	0.001	0.998	0.160	0.540	−0.237	0.359
	ACC	HC	−0.216	0.405	−0.086	0.790	–	–	0.241	0.352	0.089	0.733	–	–	–	–
		CP	−0.053	0.840	−0.660	0.004*	−0.217	0.402	−0.136	0.603	−0.192	0.461	−0.139	0.594	0.086	0.742
	dlPFC	HC	−0.140	0.593	−0.135	0.676	–	–	−0.163	0.533	−0.067	0.799	–	–	–	–
		CP	−0.007	0.980	−0.023	0.931	−0.009	0.973	0.081	0.756	0.249	0.335	0.271	0.293	−0.071	0.787
	Brainstem	HC	−0.208	0.423	0.147	0.648	–	–	−0.187	0.473	−0.068	0.795	–	–	–	–
		CP	−0.068	0.794	−0.364	0.151	−0.188	0.471	−0.267	0.300	−0.209	0.421	−0.292	0.256	0.027	0.918
	mPFC	HC	−0.249	0.334	0.090	0.781	–	–	0.061	0.815	0.028	0.916	–	–	–	–
		CP	−0.021	0.937	−0.388	0.124	0.019	0.941	0.059	0.822	−0.071	0.785	0.137	0.601	−0.321	0.209
	NAc	HC	−0.296	0.249	−0.124	0.700	–	–	−0.006	0.983	0.058	0.824	–	–	–	–
		CP	0.182	0.485	−0.360	0.156	−0.256	0.321	−0.295	0.250	−0.140	0.592	−0.122	0.640	0.154	0.556
%ΔOA		CP	–		−0.083	0.751	0.223	0.389	0.279	0.278	0.247	0.340	0.178	0.493	−0.079	0.762

OA: offset analgesia; BOLD: blood oxygen level-dependent; HC: healthy control; CP: patients with chronic pain; ROI: region of interest; R: correlation coefficient; PD-Q: PainDETECT questionnaire; PCS: Pain Catastrophizing Scale; BDI: Beck Depression Inventory; SF-MPQ: Short-Form McGill Pain Questionnaire; VAS: visual analogue scale; ACC: anterior cingulate cortex; dlPFC: dorsolateral prefrontal cortex; mPFC: medial prefrontal cortex; NAc: nucleus accumbens.

*Statistically significant at p < 0.05.