Table 2. Comparison of clinical and biochemical characteristics according to brain magnetic resonance imaging findings.
| Boys | ||||
|---|---|---|---|---|
| Total (n = 138) |
A | B | P-value | |
| (n = 128) | (n = 10) | |||
| Age at CPP diagnosis (years) | 9.51 ± 0.56 | 9.52 ± 0.58 | 9.46 ± 0.29 | 0.12 |
| Height (SDS) | 1.14 ± 1.23 | 1.14 ± 1.22 | 1.14 ± 1.35 | 0.98 |
| Weight (SDS) | 1.12 ± 0.82 | 1.12 ± 0.82 | 1.05 ± 0.82 | 0.73 |
| BMI (SDS) | 0.87 ± 0.85 | 0.88 ± 0.85 | 0.77 ± 0.85 | 0.80 |
| Tanner stage | ||||
| Testicular volume | 5.28 ± 1.78 | 5.27 ± 1.77 | 5.30 ± 2.11 | 0.80 |
| Pubic hair | 1.30 ± 0.53 | 1.30 ± 0.52 | 1.30 ± 0.68 | 0.76 |
| Bone age (SDS) | 3.50 ± 1.33 | 3.53 ± 1.34 | 3.06 ± 1.14 | 0.39 |
| Basal LH (mIU/mL) | 1.00 ± 1.21 | 1.00 ± 1.24 | 1.00 ± 0.77 | 0.55 |
| Basal FSH (mIU/mL) | 3.24 ± 7.50 | 3.25 ± 7.78 | 3.12 ± 1.40 | 0.12 |
| Peak LH (mIU/mL) | 16.67 ± 9.36 | 16.50 ± 9.12 | 18.70 ± 12.44 | 0.81 |
| Testosterone (ng/mL) | 0.66 ± 1.19 | 0.65 ± 1.21 | 0.69 ± 0.94 | 0.57 |
A: Group with normal findings on brain magnetic resonance imaging. B: Group with new abnormal findings on brain magnetic resonance imaging. BMI: body mass index, CPP: central precocious puberty, FSH: follicle stimulating hormone, LH: luteinizing hormone, SDS: standard deviation score