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. 2018 Apr 3;13(4):e0194828. doi: 10.1371/journal.pone.0194828

Table 2. Predicted and observed group membership using a classification tree model with intrathecal IgG production and NFL.

The formula for age adjusted NFL is given by NFL– 203.3–15.9 * Age (y), as estimated by linear regression in healthy controls.

Decision rule Observed
SC RRMS OD
SC: No intrathecal IgG production and Age adjusted NFL < 148 77 2 16
OD/RRMS:No intrathecal IgG production and Age adjusted NFL ≥ 148 1 3 8
RRMS/OD: Intrathecal IgG production 3 66 9

IgG = immoglobulin G, NFL = neurofilament light, RRMS = relapsing remitting multiple sclerosis, SC = symptomatic controls, OD = patients with other disease