Fig 2. Dysregulated cePathways suggest NGF-induced cell proliferation.

(a). Growth factor pathways that gained cePathway relationship in tumors with NGF signaling pathways in the TCGA data (red) and in GSE57297[19] (purple). (b). Behavior of running sum between Reactome “signaling by NGF” pathway and KEGG “TGFβ signaling” pathway. Gray lines represent running sum of 50 random trials (Actual p-values are estimated from 2,000 such random trials).