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The pharmacological effects of evocalcet and cinacalcet on the serum PTH (A; evocalcet, C; cinacalcet) and calcium (B; evocalcet, D; cinacalcet) levels in normal rats. Vehicle, evocalcet (0.03, 0.1, 0.3, or 1 mg/kg), or cinacalcet (1, 3, 10, or 30 mg/kg) were orally administered to the rats. The data are presented as the mean + S.E. n = 10/group. aP < 0.05, bP < 0.01, and cP < 0.001 vs. Vehicle group (Steel test).
