Table 1. Pharmacokinetic parameters of evocalcet after oral administration to male rats.

Dose	Cmax			tmax			AUC0-∞			t1/2			F
(mg/kg)	(ng/mL)			(h)			(ng⋅h/mL)			(h)			(%)
0.1	222.2	±	19.8	0.25	±	0.00	819	±	262	6.66	±	1.94	81.6
0.3	599.6	±	59.8	0.38	±	0.14	2578	±	403	5.77	±	0.33	85.6
1	2188	±	291	0.81	±	0.38	8445	±	1108	6.13	±	0.61	84.2

The mean ± S.D. n = 4/group. F, bioavailability