Table 3. The effects of evocalcet and cinacalcet on emesis in common marmosets.
Treatment | Minimum effective dose on PTH reduction (μg/kg) | Dosage (μg/kg) |
Number of emesis | Safety margin |
---|---|---|---|---|
Evocalcet | 5 | 50 | 0/6 | 10 < X < 30 |
150 | 1/6 | |||
Cinacalcet | 500 | 1500 | 0/6 | 3 < X < 10 |
5000 | 5/6 |