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. 2013 Sep 6;4:2399. doi: 10.1038/ncomms3399

Figure 4. TRPA1b overexpression in WT DRG cells enhanced the AITC- but not the capsaicin-evoked increase in the fura-2 ratio.

Figure 4

(a) Changes in the fura-2 ratio in vector-introduced (Control, upper) and TRPA1b-introduced (lower) DRG neurons from WT mice. Black bars indicate agonist application periods. Responses to TRPA1 alone (blue), TRPV1 alone (red), and TRPA1 with TRPV1 (green) are shown. (b) AITC and Cap responses (normalized to the ionomycin responses) were compared. Data represent mean±s.e.m. **P<0.01, Control n=343; TRPA1b n=308, unpaired Student’s t-test. (c) Summary of AITC- and Cap-positive cell populations from vector-introduced (Control, left) and TRPA1b-introduced (right) DRG neurons.