Table 3.
A. BOYS | Model 1 | Model 2 | Model 3 | Model 4 | ||||||||
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Middle vs Lower trajectory group | OR | 95%CI | P value | OR | 95%CI | P value | OR | 95%CI | P value | OR | 95%CI | P value |
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Birth weight(z score) | 1.02 | 0.76–1.38 | 0.8736 | 0.99 | 0.73–1.35 | 0.9738 | 0.77 | 0.6–0.98 | 0.0307 | 0.75 | 0.58–0.96 | 0.0223 |
Relative weight gain in infancy | 1.54 | 1.14–2.09 | 0.0050 | 1.65 | 1.2–2.26 | 0.0021 | 1.21 | 0.95–1.55 | 0.1237 | 1.23 | 0.96–1.59 | 0.1046 |
Relative weight gain in mid-childhood | 1.20 | 0.94–1.54 | 0.1522 | 1.28 | 0.96–1.7 | 0.0918 | 1.25 | 0.99–1.57 | 0.0653 | 1.26 | 0.98–1.62 | 0.0712 |
Relative linear growth in infancy | 1.76 | 1.28–2.43 | 0.0005 | 1.72 | 1.26–2.35 | 0.0007 | 0.84 | 0.64–1.11 | 0.2157 | 0.84 | 0.64–1.11 | 0.2299 |
Relative linear growth in mid-childhood | 1.65 | 1.24–2.18 | 0.0005 | 1.58 | 1.19–2.11 | 0.0018 | 0.85 | 0.67–1.09 | 0.2021 | 0.89 | 0.7–1.15 | 0.3774 |
Upper vs Lower trajectory group | ||||||||||||
Birth weight(z score) | 1.03 | 0.7–1.51 | 0.8705 | 1.02 | 0.66–1.56 | 0.9453 | 0.69 | 0.31–1.55 | 0.3652 | 0.67 | 0.28–1.61 | 0.3685 |
Relative weight gain in infancy | 1.58 | 1.08–2.33 | 0.0190 | 1.67 | 1.09–2.56 | 0.0196 | 3.74 | 1.43–9.83 | 0.0074 | 4.11 | 1.25–13.51 | 0.0202 |
Relative weight gain in mid-childhood | 1.34 | 0.95–1.89 | 0.0950 | 1.36 | 0.92–2.02 | 0.1221 | 1.21 | 0.59–2.48 | 0.6088 | 1.20 | 0.54–2.65 | 0.6604 |
Relative linear growth in infancy | 2.15 | 1.41–3.28 | 0.0004 | 2.18 | 1.39–3.43 | 0.0007 | 1.62 | 0.67–3.93 | 0.2847 | 1.98 | 0.71–5.48 | 0.1912 |
Relative linear growth in mid-childhood | 1.44 | 1–2.09 | 0.0513 | 1.53 | 1.02–2.3 | 0.0400 | 1.02 | 0.44–2.34 | 0.9645 | 1.12 | 0.39–3.2 | 0.8392 |
B.GIRLS | ||||||||||||
Middle vs Lower trajectory group | ||||||||||||
Birth weight(z score) | 1.23 | 0.93–1.63 | 0.1490 | 1.12 | 0.85–1.48 | 0.4309 | 1.09 | 0.84–1.42 | 0.5190 | 0.97 | 0.73–1.28 | 0.8223 |
Relative weight gain in infancy | 1.39 | 1.04–1.86 | 0.0276 | 1.37 | 1.02–1.85 | 0.0350 | 1.33 | 1.02–1.75 | 0.0378 | 1.33 | 1–1.76 | 0.0492 |
Relative weight gain in mid-childhood | 1.00 | 0.75–1.32 | 0.9802 | 1.09 | 0.81–1.46 | 0.5669 | 1.11 | 0.85–1.44 | 0.4507 | 1.22 | 0.93–1.59 | 0.1546 |
Relative linear growth in infancy | 2.11 | 1.51–2.94 | 0.0000 | 2.07 | 1.48–2.91 | 0.0000 | 1.60 | 1.15–2.21 | 0.0053 | 1.58 | 1.15–2.17 | 0.0046 |
Relative linear growth in mid-childhood | 1.14 | 0.87–1.49 | 0.3394 | 1.12 | 0.85–1.48 | 0.4209 | 1.03 | 0.79–1.36 | 0.8098 | 1.01 | 0.75–1.35 | 0.9578 |
Upper vs Lower trajectory group | ||||||||||||
Birth weight(z score) | 1.34 | 0.93–1.94 | 0.1123 | 1.31 | 0.89–1.92 | 0.1682 | 1.35 | 0.94–1.94 | 0.1043 | 1.27 | 0.86–1.88 | 0.2246 |
Relative weight gain in infancy | 1.67 | 1.14–2.44 | 0.0085 | 1.59 | 1.06–2.37 | 0.0236 | 1.69 | 1.14–2.5 | 0.0084 | 1.63 | 1.08–2.46 | 0.0211 |
Relative weight gain in mid-childhood | 1.65 | 1.18–2.31 | 0.0038 | 1.76 | 1.22–2.55 | 0.0026 | 1.69 | 1.2–2.38 | 0.0026 | 1.77 | 1.22–2.56 | 0.0025 |
Relative linear growth in infancy | 2.35 | 1.59–3.48 | 0.0000 | 2.23 | 1.48–3.35 | 0.0001 | 1.98 | 1.33–2.96 | 0.0008 | 1.90 | 1.27–2.86 | 0.0019 |
Relative linear growth in mid-childhood | 1.95 | 1.37–2.78 | 0.0002 | 1.99 | 1.36–2.91 | 0.0004 | 2.03 | 1.38–2.99 | 0.0003 | 2.12 | 1.39–3.23 | 0.0005 |
The multinomial logistic regression showing odds ratios, 95% confidence intervals and the p values from GBTM showing:
Model 1: Multinomial logistic regression of growth variables and SBP trajectory classes adjusted for gestational age (time-invariant covariate-a proxy for intrauterine environment).
Model 2: Multinomial logistic regression of growth variables and SBP trajectory classes adjusted for gestational age, parity, SES in infancy, maternal age (time-invariant covariates-intrauterine environment and maternal factors).
Model 3: Multinomial logistic regression of growth variables and SBP trajectory classes with height as time-varying covariate (a marker of childhood environment) and gestational age as a time-invariant covariate.
Model 4: Multinomial logistic regression of growth variables and SBP trajectory classes with height as time varying covariate and gestational age, parity, SES in infancy, and maternal age as a time-invariant covariates.