Table 1. SLAM members implicated in hematological affections and targeted by diagnosis and therapeutic strategies.
| SLAM Family | Cancer | Expression | References |
|---|---|---|---|
| SLAMF1 | MM | ↘ | [23] |
| CLL | ↘ | [24] | |
| ALL | Unmodified | [27] | |
| B lymphoma | ↗ | [28] | |
| Hodgkin’s lymphoma | ↗ | [30] | |
| Non-Hodgkin’s Lymphoma | Unmodified | [29] | |
| SLAMF2 | CLL | Unmodified | [35] |
| B lymphoma | Unmodified | [36] | |
| MM | ↗ | [37] | |
| SLAMF3 | B-CLL | ↗ | [49] |
| MM | ↗ | [50] | |
| SLAMF4 | AML | Unmodified | [55] |
| SLAMF5 | CLL | ↗ | [62] |
| SLAMF6 | CLL | ↗ | [67] |
| Lymphoma | ↗ | [67] | |
| SLAMF7 | MM | ↗ | [70] |
Abbreviations: MM: Multiple Myeloma; CLL: Chronic Lymphocytic Leukemia; ALL: Acute Lymphocytic Leukemia; AML: Acute Myeloid Leukemia.