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. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: Mol Cancer Res. 2018 Jan 12;16(4):669–681. doi: 10.1158/1541-7786.MCR-17-0321

Figure 2. The miR-888 cluster modulated hormone-sensitive and castration-resistant prostate cancer cell proliferation.

Figure 2

WST-1 assays were performed 24, 48, and 72 h post-transfection in (A) PC3-N and (B) LNCaP prostate cells treated individually with miR-888 cluster miRNA mimics (50 nM) compared to cells treated with negative SCR (scrambled) control mimics (50 nM). miR-888, miR-891b, miR-891a (and to an extent miR-892a) induced PC3-N growth, whereas miR-892c or miR-890 treatment decreased proliferation. In LNCaP cells, miR-891a, miR-892a, or miR-892b overexpression showed significant growth.