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. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: Mol Cancer Res. 2018 Jan 12;16(4):669–681. doi: 10.1158/1541-7786.MCR-17-0321

Figure 5. miR-888 and miR-891a promoted tumor growth in mice.

Figure 5

A, PC3-N cell lines stably expressing miR-888 (mixed 1:1 with Matrigel) were implanted subcutaneously into the right flanks of male NOD/SCID mice (n = 10). PC3-N cells stably expressing SCR mimics (mixed 1:1 with Matrigel) were implanted into the left flanks of these same animals. miR-888 tumors grew faster than SCR control tumors (left panel). Mice were sacrificed 5 weeks post-injection. Dissected miR-888 tumors (middle panel) weighed more than SCR tumors (right panel). B, Similar mouse xenograft results were found for miR-891a (n = 5).