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. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: Cell Signal. 2018 Feb 21;46:15–22. doi: 10.1016/j.cellsig.2018.02.009

Figure 2.

Figure 2

FBW7 ubiquitin substrates and their critical roles in cellular metabolism. FBW7 is capable of governing various metabolic pathways through promoting the degradation of key substrates such as c-Myc, HIF-1α, SREBP, PGC-1α, mTOR, and REV-ERBα, respectively.