Table 4.
Multivariable associations of body mass index, waist circumference, and waist-hip ratio with mobility and survival status stratified by age at total knee replacement for osteoarthritis*
| Survived to age 85 with mobility limitation
|
Died before age 85
|
|||
|---|---|---|---|---|
| No. survived to 85 with mobility limitation/total (%) | Multivariable-adjusted† OR (95% CI) |
No. died before 85/total (%) | Multivariable-adjusted† OR (95% CI) |
|
| Age 67–74 years‡ | ||||
| Body mass index, kg/m2 | ||||
| Normal (≤24.9) | 27/75 (36.0) | 1 [Ref] | 17/75 (22.7) | 1 [Ref] |
| Overweight (25.0–29.9) | 71/154 (46.1) | 1.95 (0.97–3.91) | 38/154 (24.7) | 1.97 (0.83–4.66) |
| Obese I (30.0–34.9) | 66/144 (45.8) | 2.75 (1.30–5.82) | 54/144 (37.5) | 4.36 (1.80–10.54) |
| Obese II (≥35.0) | 47/117 (40.2) | 3.24 (1.40–7.50) | 55/117 (47.0) | 5.73 (2.19–14.97) |
| Waist circumference, cm | ||||
| ≤88 | 81/185 (43.8) | 1 [Ref] | 37/185 (20.0) | 1 [Ref] |
| >88 | 132/307 (43.0) | 1.88 (1.14–3.10) | 127/307 (41.4) | 3.77 (2.08–6.83) |
| Age 75–79 years§ | ||||
| Body mass index, kg/m2 | ||||
| Normal (≤24.9) | 76/181 (42.0) | 1 [Ref] | 39/181 (21.6) | 1 [Ref] |
| Overweight (25.0–29.9) | 146/323 (45.2) | 0.96 (0.61–1.49) | 72/323 (22.3) | 0.99 (0.56–1.74) |
| Obese I (30.0–34.9) | 124/220 (56.4) | 1.60 (0.97–2.65) | 43/220 (19.6) | 0.92 (0.47–1.78) |
| Obese II (≥35.0) | 78/141 (55.3) | 1.99 (1.10–3.62) | 38/141 (27.0) | 1.58 (0.75–3.32) |
| Waist circumference, cm | ||||
| ≤88 | 177/410 (43.2) | 1 [Ref] | 91/410 (22.2) | 1 [Ref] |
| >88 | 252/460 (54.8) | 1.55 (1.10–2.18) | 101/460 (22.0) | 0.95 (0.61–1.47) |
| Age 80–82 years¶ | ||||
| Body mass index, kg/m2 | ||||
| Normal (≤24.9) | 56/123 (45.5) | 1 [Ref] | 6/123 (4.9) | 1 [Ref] |
| Overweight (25.0–29.9) | 102/215 (47.4) | 1.32 (0.81–2.15) | 25/215 (11.6) | 3.44 (1.18–10.02) |
| Obese (≥30.0) | 89/154 (57.8) | 1.78 (1.03–3.06) | 17/154 (11.0) | 3.78 (1.23–11.67) |
| Waist circumference, cm | ||||
| ≤88 | 119/263 (45.3) | 1 [Ref] | 22/263 (8.4) | 1 [Ref] |
| >88 | 129/230 (56.1) | 1.61 (1.07–2.43) | 26/230 (11.3) | 1.61 (0.79–3.28) |
CI = confidence interval; OR = odds ratio.
Reference group is survived to age 85 with intact mobility.
Adjusted for study membership, education, race/ethnicity, baseline marital status, baseline alcohol consumption, baseline smoking status, baseline total physical activity, total number of chronic diseases, hormone therapy use, baseline depression, second total knee replacement, and total hip replacement.
P for trend (BMI): 1. Survived to age 85 with mobility limitation = 0.007. 2. Died before 85 = <0.001.
P for trend (waist circumference): 1. Survived to age 85 with mobility limitation = 0.01. 2. Died before 85 = <0.001.
P for trend (BMI): 1. Survived to age 85 with mobility limitation = 0.01. 2. Died before 85 = 0.30.
P for trend (waist circumference): 1. Survived to age 85 with mobility limitation = 0.002. 2. Died before 85 = 0.38.
P for trend (BMI): 1. Survived to age 85 with mobility limitation = 0.02. 2. Died before 85 = 0.22.
P for trend (waist circumference): 1. Survived to age 85 with mobility limitation = 0.002. 2. Died before 85 = 0.23.