Table 1.
Patient and tumor characteristics
| All cases, n (%) | DIA casesa, n (%) | |||
|---|---|---|---|---|
| Total | 154 | (100) | 117 | (100) |
| Gender | ||||
| Female | 151 | (98.1) | 115 | (98.3) |
| Male | 3 | (1.9) | 2 | (1.7) |
| Age (years) | ||||
| < 60 | 74 | (48.1) | 56 | (47.9) |
| ≥ 60 | 80 | (51.9) | 61 | (52.1) |
| Mean | 60.4 | 60.5 | ||
| Histologic type | ||||
| Ductal/no special type | 132 | (85.7) | 101 | (86.3) |
| Lobular | 22 | (14.3) | 16 | (13.7) |
| Histologic grade | ||||
| G1 | 37 | (24.0) | 28 | (23.9) |
| G2 | 75 | (48.7) | 57 | (48.7) |
| G3 | 42 | (27.3) | 32 | (27.4) |
| Tumor diameter (cm) | ||||
| ≤ 2 | 102 | (66.2) | 80 | (68.4) |
| > 2 and ≤ 5 | 42 | (27.3) | 30 | (25.6) |
| > 5 | 10 | (6.5) | 7 | (6.0) |
| Mean | 2.1 | 2.0 | ||
| ER | ||||
| Positive | 133 | (86.4) | 100 | (85.5) |
| Negative | 21 | (13.6) | 17 | (14.5) |
| PR | ||||
| Positive | 118 | (76.6) | 92 | (78.6) |
| Negative | 36 | (23.4) | 25 | (21.4) |
| HER2 | ||||
| Positive | 15 | (9.7) | 9 | (7.7) |
| Negative | 137 | (89.0) | 106 | (90.6) |
| Equivocal | 2 | (1.3) | 2 | (1.7) |
DIA digital image analysis, ER estrogen receptor, PR progesterone receptor, HER2 human epidermal growth factor 2
a37 cases were excluded from further analysis due to misalignment of the virtual dual staining