Table 3.
The CT features of wild-type and mutation subtypes
| Characteristics | Total | Wild-type | Mutation | P | |||
|---|---|---|---|---|---|---|---|
| 18 | 19 | 20 | 21 | ||||
| Density (HU) | |||||||
| Non-enhanced | 34.089 ± 9.449 | 34.333 ± 6.351 | 33.136 ± 11.235 | 37.667 ± 8.824 | 31.936 ± 10.182 | 0.675 | |
| Enhanced | 60.946 ± 13.770 | 51.000 ± 8.660 | 60.250 ± 14.379 | 58.833 ± 9.621 | 57.553 ± 14.359 | 0.599 | |
| Erel | 0.180 ± 0.079 | 0.126 ± 0.013 | 0.197 ± 0.099 | 0.166 ± 0.086 | 0.160 ± 0.065 | 0.002 | |
| Size (mm) | |||||||
| MaxD mediastinal | 39.125 (6–109) | 23.000 (11–30) | 29.727 (6–75) | 26.000 (14–45) | 29.894 (3–88) | 0.032 | |
| MinD mediastinal | 31.518 (5–93) | 21.000 (11−26) | 23.864 (4–52) | 22.333 (10–42) | 22.809 (2–50) | 0.160 | |
| MaxD lung | 40.714 (7–139) | 24.333 (15–30) | 34.409 (13–92) | 31.167 (15–45) | 33.574 (11–101) | 0.271 | |
| MinD lung | 32.875 (6–99) | 22.333 (15–26) | 27.273 (11–61) | 28.000 (12–46) | 26.250 (9–52) | 0.311 | |
| TDR | 0.071 (0–0.443) | 0.154 (0–0.462) | 0.206 (0–0.926) | 0.267 (0–0.701) | 0.197 (0–0.962) | 0.042 | |
| Lobulation | 4.589 ± 3.431 | 2.333 ± 2.082 | 4.341 ± 2.745 | 6.167 ± 1.835 | 4.745 ± 3.473 | 0.509 | |
| Homogeneity after contrast | 0.125 | ||||||
| Heterogeneous | 65 | 30 | 0 | 16 | 3 | 16 | |
| Homogenous | 91 | 26 | 3 | 28 | 3 | 31 | |
| GGO | 0.034 | ||||||
| Present | 36 | 5 | 1 | 15 | 2 | 13 | |
| Absent | 120 | 51 | 2 | 29 | 4 | 34 | |
| Pericardial effusion | 0.897 | ||||||
| Present | 5 | 1 | 0 | 2 | 0 | 2 | |
| Absent | 151 | 55 | 3 | 42 | 6 | 45 | |
| Location | 0.164 | ||||||
| Inferior lobe of left lung | 34 | 17 | 0 | 8 | 0 | 9 | |
| Superior lobe of left lung | 29 | 8 | 1 | 9 | 2 | 9 | |
| Middle lobe of right lung | 10 | 2 | 0 | 0 | 1 | 7 | |
| Inferior lobe of right lung | 52 | 21 | 1 | 13 | 2 | 15 | |
| Superior lobe of right lung | 31 | 8 | 1 | 14 | 1 | 7 | |
| Pneumonia-type | 0.415 | ||||||
| Pneumonia-type | 5 | 0 | 0 | 2 | 0 | 3 | |
| Non-pneumonia-type | 151 | 56 | 3 | 42 | 6 | 44 | |
| Shape | 0.400 | ||||||
| Round or oval | 110 | 40 | 3 | 34 | 4 | 29 | |
| Irregular | 46 | 16 | 0 | 10 | 2 | 18 | |
| Spiculation | 0.899 | ||||||
| Present | 108 | 37 | 2 | 30 | 5 | 34 | |
| Absent | 48 | 19 | 1 | 14 | 1 | 13 | |
| Boundary | 0.103 | ||||||
| Clear | 146 | 52 | 3 | 38 | 6 | 47 | |
| Obscure | 10 | 4 | 0 | 6 | 0 | 0 | |
| Calcification | 0.435 | ||||||
| Present | 9 | 5 | 0 | 2 | 1 | 1 | |
| Absent | 147 | 51 | 3 | 42 | 5 | 46 | |
| Cavitation | 0.960 | ||||||
| Present | 27 | 9 | 1 | 8 | 1 | 8 | |
| Absent | 129 | 47 | 2 | 36 | 5 | 39 | |
| Air bronchogram | 0.206 | ||||||
| Present | 38 | 10 | 0 | 7 | 3 | 18 | |
| Absent | 118 | 46 | 3 | 37 | 3 | 29 | |
| Vascular convergence sign | 0.116 | ||||||
| Present | 57 | 14 | 2 | 18 | 4 | 19 | |
| Absent | 99 | 42 | 1 | 26 | 2 | 28 | |
| Pleural indentation | 0.652 | ||||||
| Present | 95 | 33 | 1 | 25 | 4 | 32 | |
| Absent | 61 | 23 | 2 | 19 | 2 | 15 | |
| Pleural effusion | 0.381 | ||||||
| Present | 15 | 3 | 0 | 7 | 0 | 5 | |
| Absent | 141 | 53 | 3 | 37 | 6 | 42 | |
| Mediastinal lymph node metastasis | 0.550 | ||||||
| Present | 57 | 24 | 1 | 16 | 3 | 13 | |
| Absent | 99 | 32 | 2 | 28 | 3 | 34 | |