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Detection of BaP metabolites on HPLC from in vitro incubations with BaP and hepatic microsomal fractions from BaP-pretreated WT, HRN and HBRN mice using either NADPH or NADH as cofactor. Values are given as mean ± SD (n = 3). Statistical analysis was performed by one-way ANOVA with Tukey’s multiple comparison test (*, compared to WT; #, compared to HRN. *P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001)
