Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Mar 28;9:624. doi: 10.3389/fimmu.2018.00624

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 Workman, Maina, Brooks, Kohanski, Cowart, Mansfield, Kennedy, Palmer, Adappa, Reed, Lee and Cohen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Quinine-induced nitric oxide (NO) release [as assessed by 4-amino-5-methylamino-2′,7′-difluorescein (DAF-FM)] is significantly attenuated by U73122, a phospholipase C β2 blocker, which is necessary for T2R-mediated signaling. This attenuation is not observed with incubation with U73343, an inactive analog of U73122 (n = 6–9 cultures). (A) NO release over a period of 5 min, and (B) maximal NO release during that same period. *p < 0.05, **p < 0.01.