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. 2018 Apr 3;8:5579. doi: 10.1038/s41598-018-23904-3

Table 3.

Determinants of health status in sleep study participants (sleep study group). Coefficients and 95% confidence intervals (95% CI) for SF-36 scales according to categories of obstructive sleep apnea severity. Multivariable linear regression adjusted for gender, education, age, body mass index, Epworth sleepiness scale score > 10 as well as presence of high blood pressure, diabetes and anxiety or depression.

Physical functioning (N = 304) Vitality (N = 304) Physical component summary (N = 304) Mental component summary (N = 304)
Coef.* 95% CI P Coef.* 95% CI P Coef.* 95% CI P Coef.* 95% CI P
Obstructive sleep apnea
    Normal (AHI** < 5) 0
    Mild (AHI** 5–14) −0.7 −5.1–3.7 0.76 −0.6 −6.1–4.8 0.82 −0.8 −3.6–2.1 0.60 0.1 −2.5–2.7 0.95
    Moderate (AHI** 15–29) 4.1 −1.2–9.4 0.126 3.4 −4.6–11.2 0.41 0.4 −3.5–4.4 0.83 1.4 −2.0–4.8 0.43
    Severe (AHI** > 30) −0.1 −7.1–6.8 0.98 1.9 −8.1–9.0 0.92 −1.1 −5.1–2.9 0.59 1.4 −1.7–4.5 0.36
    Female gender −3.6 −8.3–1.0 0.128 −2.0 −7.3–3.2 0.45 −0.9 −3.8–1.9 0.53 −1.9 −4.5–0.67 0.147
Education
    Schooling up to 10 years 0
    Schooling 11–13 years 2.2 −3.7–8.1 0.47 1.9 −5.5–9.3 0.61 0.6 −3.0–4.2 0.74 0.3 −2.7–3.3 0.84
    University or college degree 3.2 −2.8–9.2 0.29 1.9 −5.4–9.1 0.62 0.1 −3.3–3.5 0.94 −1.0 −3.8–1.8 0.48
Age per 10 years −1.1 −3.0–0.7 0.24 4.4 2.1–6.6 <0.001 −0.3 −1.3–0.8 0.64 1.85 0.8–2.9 <0.001
Body mass index, kg/m2 −0.8 −1.3–−0.3 0.001 0.4 −0.1–1.0 0.122 −0.1 −0.4–0.1 0.31 0.2 −0.06–0.4 0.143
Epworth Sleepiness Scale > 10 −1.0 −5.0–3.0 0.63 −9.7 −14.3–−5.1 <0.001 −1.2 −3.7–1.3 0.34 −1.2 −3.1–0.8 0.25
High blood pressure −5.2 −11.4–1.0 0.101 −2.0 −9.1–5.2 0.59 −3.8 −6.8–−0.7 0.016 0.3 −2.4–3.1 0.81
Diabetes mellitus −9.9 −19.6–−0.3 0.043 −7.8 −16.9–1.4 0.098 −3.8 −8.9–1.2 0.135 −1.6 −5.6–2.5 0.45
Anxiety or depression −4.1 −9.9–1.7 0.163 −12.1 −18.3–−5.8 <0.001 −1.3 −4.2–1.6 0.38 −12.7 −15.7–−9.6 <0.001

*Unstandardized beta coefficient.

**Apnea-hypopnea index.