Table 1.
Haemodynamic changes during a 25 min occlusion of the LAD.
| Saline | NaNO2 | |||
|---|---|---|---|---|
| Baseline | Max. change | Baseline | Max. change | |
| SABP (mmHg) | 145 ± 14 | −17 ± 3* | 141 ± 4 | −10 ± 5* |
| DABP (mmHg) | 101 ± 10 | −18 ± 3* | 97 ± 4 | −11 ± 6* |
| MABP (mmHg) | 116 ± 11 | −17 ± 2* | 111 ± 3 | −11 ± 5* |
| LVSP (mmHg) | 139 ± 11 | −25 ± 5* | 143 ± 13 | −9 ± 6* |
| LVEDP (mmHg) | 6.6 ± 1.0 | 7.1 ± 1.4* | 4.4 ± 1.6 | 5.4 ± 0.7*# |
| +dP/dtmax(mmHg/s) | 2869 ± 226 | −769 ± 78* | 2839 ± 138 | −557 ± 148* |
| −dP/dtmax (mmHg/s) | 2609 ± 163 | −574 ± 193* | 2295 ± 63 | −147 ± 118*# |
| HR (beats/min) | 168 ± 7 | 5 ± 5 | 165 ± 8 | −5 ± 2 |
Mean ± SEM, calculated from n = 10 experiments.
*
P < 0.05 vs. baseline value,
#
P < 0.05 vs. saline treated control group.
SABP, systolic arterial blood pressure; DABP, diastolic arterial blood pressure; MABP, mean arterial blood pressure; LVSP, left ventricular systolic pressure; LVEDP, left ventricular end-diastolic pressure; HR, heart rate.