Table 2.
Morphological changes in the different mitochondria subsets following ischaemia and reperfusion, and sodium nitrite administration.
Area (μm2) | Perimeter (μm) | Feret diameter (μm) | Roundness | |
---|---|---|---|---|
SC (n = 4) | ||||
SSM | 0.48 ± 0.02 | 2.69 ± 0.03 | 1.04 ± 0.01 | 0.57 ± 0.05 |
IMF | 0.68 ± 0.04 | 3.38 ± 0.06 | 1.37 ± 0.03 | 0.46 ± 0.03 |
PN | 0.49 ± 0.02 | 2.77 ± 0.09 | 1.09 ± 0.04 | 0.58 ± 0.02 |
IC (n = 6) | ||||
SSM | 0.35 ± 0.02* | 2.12 ± 0.05* | 0.77 ± 0.02* | 0.75 ± 0.01* |
IMF | 0.39 ± 0.04* | 2.30 ± 0.08* | 0.88 ± 0.03* | 0.67 ± 0.03* |
PN | 0.39 ± 0.02* | 2.26 ± 0.05* | 0.82 ± 0.02* | 0.75 ± 0.02* |
NaNO2-IC (n = 4) | ||||
SSM | 0.65 ± 0.05# | 3.15 ± 0.12# | 1.22 ± 0.07# | 0.58 ± 0.07# |
IMF | 0.54 ± 0.04# | 2.88 ± 0.06# | 1.13 ± 0.01# | 0.53 ± 0.04# |
PN | 0.51 ± 0.02# | 2.76 ± 0.05# | 1.04 ± 0.02# | 0.65 ± 0.02# |
NaNO2 (n = 4) | ||||
SSM | 0.58 ± 0.06# | 2.96 ± 0.15# | 1.13 ± 0.05# | 0.58 ± 0.02# |
IMF | 0.67 ± 0.08# | 3.18 ± 0.19# | 1.22 ± 0.03# | 0.54 ± 0.01# |
PN | 0.47 ± 0.02# | 2.64 ± 0.08# | 1.02 ± 0.03# | 0.60 ± 0.02# |
For each n, 5 images were evaluated and averaged. Values are means ± S.E.M.
P < 0.05 compared with SC;
P < 0.05 compared with IC.
SSM, sub-sarcolemmal; IMF, inter-myofibrillar; PN, perinuclear.