Table 1.
Major characteristics of included studies.
| First author | Year | Country | Ethnicity | Source of control | Age (Case/Control) | Sample size (Case/Control) | Genotyping method | P for HWE |
|---|---|---|---|---|---|---|---|---|
| miR-146a C>G (rs2910164) | ||||||||
| Liu | 2014 | China | Asian | Healthy | 67.52 ± 10.29/66.34 ± 11.07 | 296/391 | PCR-RFLP | 0.650 |
| Zhu | 2014 | China | Asian | Healthy | 61.62 ± 0.986/62.05 ± 0.982 | 368/381 | PCR-LDR | 0.952 |
| Huang | 2015 | China | Asian | Healthy | 63 (54, 70)/61 (54, 68) | 531/531 | Taqman | 0.107 |
| Qu | 2016 | China | Asian | Healthy | 61.30 ± 9.40/59.50 ± 8.50 | 1,139/1,585 | PCR-LDR | <0.01 |
| Luo | 2017 | China | Asian | Healthy | 60.70 ± 12.33/60.17 ± 10.32 | 298/303 | PCR | 0.672 |
| miR-149 T>C (rs2292832) | ||||||||
| Luo | 2017 | China | Asian | Healthy | 60.70 ± 12.33/60.17 ± 10.32 | 298/303 | PCR | 0.447 |
| miR-196a2 T>C (rs11614913) | ||||||||
| Liu | 2014 | China | Asian | Healthy | 67.52 ± 10.29/66.34 ± 11.07 | 296/391 | PCR-RFLP | 0.060 |
| Zhu | 2014 | China | Asian | Healthy | 61.62 ± 0.986/62.05 ± 0.982 | 368/381 | PCR-LDR | 0.384 |
| Huang | 2015 | China | Asian | Healthy | 63 (54, 70)/61 (54, 68) | 531/531 | Taqman | 0.856 |
| Luo | 2017 | China | Asian | Healthy | 60.70 ± 12.33/60.17 ± 10.32 | 298/303 | PCR | 0.385 |
| miR-499 A>G (rs3746444) | ||||||||
| Liu | 2014 | China | Asian | Healthy | 67.52 ± 10.29/66.34 ± 11.07 | 296/391 | PCR-RFLP | 0.170 |
| Huang | 2015 | China | Asian | Healthy | 63 (54, 70)/61 (54, 68) | 531/531 | Taqman | <0.01 |
| Luo | 2017 | China | Asian | Healthy | 60.70 ± 12.33/60.17 ± 10.32 | 298/303 | PCR | 0.132 |
HWE, Hardy-Weinberg equilibrium; PCR-RFLP, polymerase chain reaction–restriction fragment length polymorphism; PCR-LDR, polymerase chain reaction-ligase detection reaction; PCR, polymerase chain reaction.