Table 5.
Overall and sensitivity analyses of miR-499 A>G (rs3746444) and risk of IS.
| Genetic model | Subgroup | No. of studies | Meta-analysis | P for Egger's test | Heterogeneity | ||
|---|---|---|---|---|---|---|---|
| OR (95%CI) | P-value | I2 (%) | P-value | ||||
| G vs. A | Overall | 3 | 1.30 (1.02–1.66) | <0.05 | 0.67 | 52.8 | 0.12 |
| HWE-Yes | 2 | 1.48 (1.20–1.83) | <0.05 | 0 | 0.84 | ||
| GG vs. AA | Overall | 3 | 1.69 (0.92–3.10) | 0.09 | – | 18.6 | 0.27 |
| HWE-Yes | 2 | 1.69 (0.92–3.10) | 0.09 | 18.6 | 0.27 | ||
| AG vs. AA | Overall | 3 | 1.35 (1.01–1.79) | <0.05 | 0.17 | 54.3 | 0.11 |
| HWE-Yes | 2 | 1.56 (1.21–2.02) | <0.05 | 0 | 0.67 | ||
| AG + GG vs. AA | Overall | 3 | 1.36 (1.02–1.80) | <0.05 | 0.36 | 56.1 | 0.10 |
| HWE-Yes | 2 | 1.58 (1.23–2.02) | <0.05 | 0 | 0.93 | ||
| GG vs. AG + AA | Overall | 3 | 1.51 (0.82–2.75) | 0.19 | – | 17.7 | 0.27 |
| HWE-Yes | 2 | 1.51 (0.82–2.75) | 0.19 | 17.7 | 0.27 | ||
OR, odds ratio; CI, confidence interval; HWE, Hardy-Weinberg equilibrium.