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. 2018 Mar 28;9:297. doi: 10.3389/fphys.2018.00297

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Copyright © 2018 Sun, Liu, Zhang, Jiao, Tan, Wang and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of overexpression of β-arrestin1 in the RVLM on cardiovascular activity in SHR. (A) According to the rat's atlas (a), green fluorescent protein (GFP) was expressed in the RVLM area (b,c). Scale bars = 200 μm in b and 50 μm in c. (B) Representative gel bands (top) and quantification bar graph (bottom) showed the protein levels of β-arrestin1 in the RVLM in the four groups. ^*P < 0.05 vs. WKY-AAV-GFP group; ^#P < 0.05 vs. SHR-AAV-GFP group. (C) Levels of MAP in the conscious groups (WKY+AAV-GFP, WKY+AAV-Arrb1, SHR+AAV-GFP, SHR+AAV-Arrb1). n = 5 per group. ^*P < 0.05 vs. SHR-AAV-GFP group; ^#P < 0.05 vs. d1.