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Effects of overexpressed β-arrestin1 on AT1R expression. Relative changes in AT1a/b mRNA (A) and protein level [B, representative gel bands (top) and quantification results (bottom)] in the RVLM in response to administration of AAV-Arrb1 in SHR vs. AAV-GFP group. No difference was detected in AT1b mRNA expression. n = 5 per group. *P < 0.05 vs. WKY-AAV-GFP group; #P < 0.05 vs. SHR-AAV-GFP group.
