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. 2018 Apr 3;8:5578. doi: 10.1038/s41598-018-23853-x

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Spatial structure of electrodes selected by thresholding PCs. In all panels the electrodes are selected with PC weights higher than 3 SDs (SELECTED). All measures on SELECTED are compared to measures on equally sized sets randomly chosen from the complementary set of the non selected electrodes (n = 100 repetitions) and the 95^th values of those bootstraps are reported (BOOTSTRAPS). All box-plots are relative to the pooling of 10 PCs and 3 experiments. Red horizontal lines are means computed across 3 experiments, boxes show the interquartile range and the whiskers correspond to the 5^th and 95^th percentiles. (a) The silhouette coefficients, a measure of goodness of spatial clustering, are significantly higher when computed on the SELECTED electrodes respect to the BOOTSTRAPS (Wilcoxon signed-rank test, n = 30, p = 10⁻⁵). (b) The mean peak cross-correlation coefficients are significantly higher among the SELECTED electrodes respect to the BOOTSTRAPS (Wilcoxon signed-rank test, n = 30, p = 10⁻⁶). (c) Similarly, the mean path length is shorter among the SELECTED electrodes respect to the BOOTSTRAPS (Wilcoxon signed-rank test, n = 30, p = 0.001). (d) Finally, the information gain, computed over the [0 100] ms time window, is higher in the SELECTED electrodes respect to the BOOTSTRAPS (Wilcoxon signed-rank test, n = 30, p = 10⁻⁶).