Table 2.
Genetic markers included in elastic net models for predicting remission.
| Gene | Marker | Chr:Position | Antidepressant | MAF | Allele |
|---|---|---|---|---|---|
| SERP1 – Intron variant | rs6794400 | 3:150581092 | Nortriptyline | 0.057 | A/C |
| TMEM170A – Intron variant | rs37596 | 16:75464422 | Nortriptyline | 0.32 | A/C |
| CFDP1 – Intron variant | rs8053632 | 16:75331042 | Nortriptyline | 0.23 | C/T |
| CCDC7 – Intron variant | rs111685823 | 10:32799271 | Nortriptyline | 0.0096 | C/T |
| TMEM2 – Intron variant | rs17057129 | 9:71698513 | Nortriptyline | 0.20 | A/C |
| SGCZ – Intron variant | rs5889536 | 8:14517210 | Nortriptyline | 0.068 | −/G |
| SLC25A37 – Intron variant | rs34841556 | 8:23556091 | Nortriptyline | 0.446 | −/CT |
| ACCN1 - Intron variant | rs8082631 | 17:34064031 | Nortriptyline | 0.42 | A/G |
| Intergenic | rs4773117 | 13:110066456 | Nortriptyline | 0.017 | C/T |
| Intergenic | rs79693177 | 2:186199515 | Nortriptyline | 0.026 | G/T |
| Intergenic | rs12874087 | 13:68211573 | Nortriptyline | 0.20 | C/T |
| Intergenic | rs2345113 | 14:56675149 | Nortriptyline | 0.15 | C/G/T |
| Intergenic | rs17091959 | 14:56691048 | Nortriptyline | 0.15 | C/T |
| Intergenic | rs10792321 | 11:61979317 | Nortriptyline | 0.40 | A/G |
| Intergenic | rs199561596 | 2:186510855 | Nortriptyline | −/AT | |
| Intergenic | rs144829540 | 2:186464172 | Nortriptyline | 0.15 | A/G |
| Intergenic | rs149619279 | 9:122105909 | Nortriptyline | 0.08 | A/G |
| Intergenic | rs34319049 | 20:38710108 | Nortriptyline | 0.03 | C/T |
| Intergenic | rs151132095 | 2:186317904 | Nortriptyline | 0.15 | C/T |
| Intergenic | rs4279984 | 11:37172240 | Nortriptyline | 0.094 | C/T |
| TMEM229B | rs28373080 | 14:67506046 | Escitalopram | 0.49 | C/T |
| CDYL – Intron variant | rs7757702 | 6:4940209 | Escitalopram | 0.45 | A/T |
| LOC105375673 – Intron variant | rs2704022 | 8:100728509 | Escitalopram | 0.42 | A/C |
| Intergenic | rs1891943 | 13:53013037 | Escitalopram | 0.13 | A/G |
| Intergenic | rs151139256 | 2:180139767 | Escitalopram | 0.026 | −/T |
| Intergenic | rs11002001 | 10:52426412 | Escitalopram | 0.014 | A/G |
| Intergenic | rs62182022 | 2:180060581 | Escitalopram | 0.15 | C/T |
| Intergenic | rs76557116 | 13:100011900 | Escitalopram | 0.47 | C/T |
| Intergenic | rs9557363 | 13:100032511 | Escitalopram | 0.47 | C/T |
| Intergenic | rs1392611 | 4:45347307 | Escitalopram | 0.16 | C/T |
| Intergenic | rs10812099 | 9:24797940 | Escitalopram | 0.23 | A/T |
MAF: Minor allele frequency.