Table 2.
Laboratory characteristics and renal pathological findings of the adult HSPN patients at biopsy
| Items | Values (n = 698) | Items | Values (n = 698) |
|---|---|---|---|
| Laboratory data | Light microscopy | ||
| Hematuria (×104/mL) | 90 (30–250) | Glomerular sclerosis (%) | 5.0 (0–13.7) |
| Urinary protein (g/day) | 0.88 (0.51–1.79) | Glomerular sclerosis >10%, n (%) | 192 (27.5) |
| <0.4 g/day, n (%) | 125 (17.9) | Segmental sclerosis (%) | 0 (0–7.1) |
| 0.4–1.0 g/day, n (%) | 256 (36.7) | Segmental sclerosis >10%, n (%) | 118 (16.9) |
| 1.0–3.5 g/day, n (%) | 250 (35.8) | Crescents (%) | 5.0 (0–12.6) |
| >3.5 g/day, n (%) | 67 (9.6) | Crescents ≥25%, n (%) | 60 (8.6) |
| Serum albumin (g/L) | 39.5 (35.4–42.8) | Glomerulus-Bowman’s capsule adhesion, n (%) | 331 (47.4) |
| Hypoproteinemia, n (%) | 65 (9.3) | Capillary necrosis, n (%) | 166 (23.8) |
| Hemoglobin (g/dL) | 13.0 ± 1.7 | Moderate and severe tubular atrophy/interstitial fibrosis, n (%) | 82 (11.7) |
| Serum creatinine (mg/dL) | 0.77 (0.63–0.97) | Immunofluorescence | |
| Blood urea nitrogen (mg/dL) | 13.3 (10.6–17.0) | IgG, n (%) | 109 (15.6) |
| Serum uric acid (µmol/L) | 333.1 ± 89.0 | IgM, n (%) | 252 (36.1) |
| Hypercholesterolemia, n (%) | 155 (22.2) | C3, n (%) | 607 (87.0) |
| C1q, n (%) | 16 (2.3) | ||
IgG, immunoglobulin G; IgM, immunoglobulin M; C3, complement 3; C1q complement 1q.