Table 4.
Factors at biopsy influencing renal survival from ESRD based on univariate and multivariate Cox Regression analyses.
| Items | Univariate | Multivariate | ||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| Hypertension | 2.971 (1.477–5.975) | P = 0.002** | — | — |
| Urinary protein >1.0 g/day | 3.693 (1.659–8.222) | P = 0.001** | 2.486 (1.087–5.685) | P = 0.031* |
| eGFR <60 mL/min/1.73 m2 | 15.556 (7.501–32.262) | P < 0.001** | 5.344 (2.297–12.433) | P < 0.001** |
| Hypoproteinemia | 3.700 (1.709–8.011) | P = 0.001** | — | — |
| Crescents ≥25% | 2.081 (0.800–5.411) | P = 0.133 | — | — |
| Glomerular sclerosis >10% | 5.778 (2.732–12.219) | P < 0.001** | 2.397 (1.026–5.603) | P = 0.044* |
| Segmental sclerosis >10% | 3.224 (1.572–6.612) | P = 0.001** | — | — |
| Moderate and severe tubular atrophy/interstitial fibrosis | 12.682 (6.235–25.795) | P < 0.001** | 5.239 (2.274–12.071) | P < 0.001** |
eGFR estimated glomerular filtration rate; HR hazard ratio; CI confidence interval.
*P < 0.05, **P < 0.01.