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. 2018 Apr 3;8:5455. doi: 10.1038/s41598-018-23683-x

Table 2.

The correlation coefficients of inhibition to anti-VP1 reactions of five enteroviruses, EV71, CA16, CB3, PV1 and RV13 by the five EV VP1 proteins among infants and children from three age groups (1–28-day, 1–12-month and 13–72-month age groups).

Coated antigens# Age group Inhibition proteins
EV71 CA16 CB3 PV1 RV13
EV71# <28d 0.767* 0.783* 0.917** 0.517
1–12 m 0.309 0.086 −0.115 0.051
13–72 m 0.354** 0.183 0.085 −0.288*
CA16# <28d −0.348 0.691* −0.003 0.083
1–12 m 0.673** 0.686** 0.710** 0.622**
13–72 m 0.194 0.336** 0.172 −0.079
CB3# <28d −0.115 0.278 0.091 0.190
1–12 m 0.226 0.265 0.493** 0.232
13–72 m 0.199 0.214* 0.104 0.158
PV1# <28d 0.722* 0.508 0.462 0.012
1–12 m −0.054 0.169 0.172 0.096
13–72 m −0.244* −0.251* 0.128 −0.348**
RV13# <28d 0.128 −0.073 −0.241 −0.368
1–12 m 0.305 0.247 0.397* 0.471*
13–72 m 0.179 0.205* 0.164 0.132

* represents p < 0.05. ** represents p < 0.001. #These coated antigens were also used as inhibition proteins.