Table 1.

Clinical data of subjects (n = 48) at baseline.

	Mean ± SD
Age (year)	29 ± 5
BMI (kg/m2)	22.5 ± 3.6
Waist circumference (cm)	76.2 ± 11.1
Fasting glucose (mmol/L)	4.5 ± 0.5
Fasting insulin (µIU/mL)	7.2 ± 4.9
HOMA-IR	1.5 ± 1.1
Total cholesterol (mmol/L)	4.4 ± 0.6
HDL cholesterol (mmol/L)	1.7 ± 0.4
Triglyceride (mmol/L)	0.7 ± 0.4
AST (U/L)	18 ± 6
ALT (U/L)	14 ± 8
eGFR (mL/min/1.73 m2)	118 ± 18
TSH (μU/mL)	1.5 ± 0.8
CRP (mg/L)	1.1 ± 1.8
BDNF (ng/mL)	21.6 ± 6.2
Work experience (month)	71 ± 62
Night-shift work experience (month)*	63 ± 62
Frequency of alcohol consumption
<1 time/month, N (%)	26 (54.2%)
≥1 time/month and <1 time/week, N (%)	17 (35.4%)
≥1 time/week, N (%)	5 (10.4%)
Frequency of coffee consumption
<1 time/day, N (%)	28 (58.3%)
≥1 time/day, N (%)	20 (41.7%)
Smoking history, N (%)	0 (0%)
Use of sedatives in the past 3 months, N (%)	2 (4.2%)
Use of anti-hypertensive drugs in the past 3 months, N (%)	0 (0%)
Exercise
<150 min/week, N (%)	46 (95.8%)
≥150 min/week, N (%)	2 (4.2%)

AST = aspartate aminotransferase, ATL = alanine aminotransferase, BDNF = brain-derived neurotrophic factor, BMI = body mass index, CRP = C-reactive protein, eGFR = estimated glomerular filtration rate, HDL = high-density lipoprotein, HOMA-IR = homeostasis model assessment of insulin resistance, TSH = thyroid stimulating hormone.

*Night-shift work experience refers to the total work experience after having worked the night shift.