Table 1.

Assay validation and physiological variability.

	Area/µm2	Ellipticity	Fibre alignment	Radial order	CCmorph
intra	1.30 (0.04)	0.039 (0.10)	0.022 (0.04)	0.007 (0.01)	0.91 (0.02)
in-donor	3.68 (0.12)	0.104 (0.25)	0.016 (0.03)	0.050 (0.10)	0.91 (0.02)
inter-donor	3.62 (0.12)	0.064 (0.16)	0.069 (0.14)	0.046 (0.09)	0.83 (0.10)

Given are the mean differences in absolute values or the respective coefficients of variation (CV, in brackets) of morphometrics between different samples for spreading area, ellipticity, fibre alignment, and radial order. The similarity between vinculin morphology plots was quantified by a normalized cross-correlation (‘CC^morph’). Intra: four independently processed samples from the same blood probe. In-donor: two samples each from repeated withdrawals from the same donor, n = 4 donors in total. Inter-donors: samples from n = 10 different donors.