Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Apr 3;8:5556. doi: 10.1038/s41598-018-23775-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Osthole has the capacity to improve haemodynamics in rats with PAH. Representative Pulse-wave Doppler echocardiographs were selected from healthy-control rats (Control group) (A), the rats with PAH induced by MCT (PAH group) (B) and osthole treated rats with PAH (osthole group) (C). RVHI was calculated according to the formula of RVHI = RV/(LV + S). mPAP (D), PASP (E) and RVHI (F) were significantly increased in the rats with PAH compared with healthy rats, and such increase was markedly restored after osthole treatment. The data represented mean ± S.E.M. (p value < 0.05 was considered as statistically different between two groups (∗ or #), and p value < 0.01 (∗∗ or ##) was regarded as significantly different between two groups; ^*,**was indicated to compare with control group; ^#,##was designed to compare with PAH group).