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. 2018 Apr 3;8:5456. doi: 10.1038/s41598-018-23691-x

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Relative activities of LDH and PDH with FX11 and DCA treatment in cells. Mean and standard deviations of the percent change in LDH and PDH activity after 48 hours of FX11 or 48 hours of DCA treatment, respectively in MCF10A cells (a) and HPDE6 cells (b) vs. vehicle. Dashed line represents enzyme activity level in vehicle-treated cells. *p < 0.05 vs. control. n = 3–5 experiments.