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. 2018 Mar 28;10:3. doi: 10.3389/fnsyn.2018.00003

FIGURE 5.

FIGURE 5

Dexamethasone significantly decreased sIPSC frequency but had no effect on mIPSC frequency. (A) Top- 20 s (top) and 2 s (bottom) of sIPSC voltage-clamp recordings representative of control (left) and Dex (right) conditions. (B) Dex significantly decreased sIPSC frequency. (C) Dex had no effect on sIPSC amplitude. (D) Time course of the Dex effect in 1-min intervals. Dex enters at 0 min and quickly decreases frequency, but not amplitude (n = 9). (E) 20 s (top) and 2 s (bottom) of mIPSC voltage-clamp recordings representative of control (TTX, left) and TTX + Dex (right) conditions. (F) Dex had no effect on mIPSC frequency. (G) Dex had no effect on mIPSC amplitude (n = 6) (p < 0.05).