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miR-532 inhibits the PI3K/Akt signaling pathway in CRC by targeting IGF-1R. SW480 and HCT116 cells were transfected with miR-NC, miR-532 mimics + pcDNA3.1 or miR-532 mimics + pcDNA3.1-IGF-1R. After transfection for 72 h, the expression levels of p-PI3K, PI3K, p-Akt and Akt were measured with western blot analysis.
