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. 2018 Mar 1;8(3):435–449.

Figure 7.

Figure 7

miR-532 inhibits CRC tumor growth in vivo by repressing IGF-1R. A. Mice were sacrificed, and the weights of the xenograft tumors from the miR-532 mimics and miR-NC groups were weighed. *P < 0.05 vs. miR-NC. B. Representative images of the miR-532 mimics and miR-NC xenograft tumors. C. The volume of the xenograft tumor from the miR-532 mimics and miR-NC groups was calculated every 2 days after inoculation for 2 weeks. *P < 0.05 vs. miR-NC. D. Expression level of miR-532 was detected in xenograft tumor tissues from the miR-532 mimics and miR-NC groups. *P < 0.05 vs. miR-NC. E. Relative protein levels of IGF-1R, p-PI3K, PI3K, p-Akt and Akt were determined in xenograft tumor tissues from the miR-532 mimics and miR-NC groups.