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. 2018 Mar 1;8(3):462–475.

Figure 2.

Figure 2

Stable knockdown of HDAC5 attenuates the proliferation of HCC cells. A. Western blot analyses of HDAC5 in THLE-3, Hep3B, and HepG2 cells. B. Western blot analyses of HDAC5, Ac-H3K9 and total H3 in Hep3B and HepG2 cells stably transfected with shHDAC5#1 and #2. C. Cell viability was measured in Hep3B and HepG2 cells with stable knockdown of HDAC5. *P<0.05; **P<0.01; ***P<0.001. D. Heatmap of qPCR arrays for proliferation and apoptosis-related genes in Hep3B with or without stable knockdown of HDAC5. Each row represents an experiment. Each column represents a gene. Red color indicates an increased expression. Green color indicates a decreased expression.