Figure 6.

High HDAC5 expression is associated with a suppressed TAp63-maspin pathway and a poor prognosis. A. Representative images of HDAC5, TAp63, and maspin immunostaining in human HCC tissues. B. The correlation among concurrent immunostaining scores of HDAC5, TAp63, and maspin in HCC tissues. C. The overall survival of HCC patients with low and high expression of TAp63 or maspin was shown. D. The schema indicating that highly expressed HDAC5 accelerates cell cycle by disrupting the TAp63-maspin pathway in HCC cells.